Creating ‘leaks’ in blood vessels could aid in drug delivery

Gang Bao, a bioengineer at Rice University, and collaborators at Emory University and the Georgia Institute of Technology report using magnets to help iron-oxide nanoparticles invade endothelial cells both in the lab and in vivo. Then they use the same magnets to make vessels temporarily “leaky.”

Fluorescent iron-oxide nanoparticles glow in endothelial cells. At left, the nanoparticles are evenly distributed among the microtubules that help give the cells their shape.  At right, after a magnetic field is applied, the nanoparticles are pulled toward one end of the cells and change their shapes.

Read more on https://geneticliteracyproject.org/2017/06/16/magnetic-drug-delivery-treatment-may-offer-better-access-deep-tissues/

You may also like...

Leave a Reply

Your email address will not be published.